toxicity
-
Chemistry
Novel platinum complex exhibits potent antiproliferative effects with low toxicity in preclinical prostate cancer models
Binuclear platinum(II) complex inhibits prostate cancer cell proliferation by binding to androgen receptor (AR) and interfering with AR-mediated gene expression. This mechanism causes apoptosis and prevents cell proliferation induced by dihydrotestosterone (DHT). Credit: Yoshihisa Hirota / SIT, Japan. DOI: 10.1021/acs.inorgchem.4c01093 Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments such…
Read More » -
Earth
Heavy metal toxicity in the ocean increases: How climate change will affect ocean pollutants
Conceptual illustration of natural and anthropogenic sources, sinks, and transport pathways of trace element pollutants in coastal ecosystems that may interact with climate change (CC) factors. Credit: Communications Earth & Environmental (2024). DOI: 10.1038/s43247-024-01679-y Toxic trace elements such as lead, mercury, arsenic, and cadmium occur naturally in small amounts in coastal waters. However, the contribution of human activities such as…
Read More »
