synthetic
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Chemistry
New synthetic technology reduces drug development time and cost
Hans Renata and Kenta Yokoi in Renata’s lab at Rice University. Credit: Alex Becker/Rice University. A team of chemists from the Scripps Research Institute and Rice University has unveiled a new method that simplifies the synthesis of piperidine, a key structural component of many pharmaceuticals. The study, published in the journal Science, combines biocatalytic carbon-hydrogen oxidation with radical cross-coupling, providing…
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Chemistry
Chemicals important for synthetic rubber production can be electrosynthesized in a sustainable way
Illustration of the electrocatalytic conversion of acetylene (C2H2) to 1,3-butadiene (C4H6) over a copper catalyst. The process involves adsorption of acetylene molecules onto the catalyst surface, followed by hydrogenation and coupling of *C2H2 and *C2H3 intermediates to form 1,3-butadiene, which is subsequently desorbed. Credit: Nature Catalysis (2024). DOI: 10.1038/s41929-024-01250-0 Chemists at the National University of Singapore (NUS) have developed a…
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Nanotechnology
Cracking the code: Researchers uncover a ‘new synthetic frontier’ for quantum dots
Colloidal solutions of gallium arsenide quantum dots, the kind used in lasers, televisions, solar cells, medical equipment and other electronics, emit light under ultraviolet light. They were grown using breakthrough technology developed by the Talapin Lab at the University of Chicago. This technique opens up a world of new materials for researchers who grow nanocrystals. Credit: University of Chicago/Talapin Lab…
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Chemistry
Use synthetic chemistry to plan the route of drugs into the body
Credit: Pixabay/CC0 Public Domain Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed a technique that allows the body to change the recognized identity of proteins. The innovation, published October 2 in Nature Communications, allows researchers to target tumors in mice with a protein and transport the protein out of the body. This means that cancer-killing drugs can…
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