smoothly

Chemistry

Researchers highlight the role ‘workhorse proteins’ play in keeping the nervous system running smoothly

Hsc70 retards SNAP-25 aggregation. Aggregation kinetics of SNAP-25 (50 μM) at 37 °C. The optical density of SNAP-25 was recorded at 360 nm in the absence (black) and presence of Hsc70 (5 μM, red) and Hsc70+CSPαJ (5 μM each, blue). Hsc70 (gray) and CSPαJ (dark gray) alone do not show aggregation. Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.108001 A…