sequence
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Biology
Introducing HORNET, a new RNA structure visualization method that correlates sequence and 3D topology
AFM images and initial models of BM3, BM4, and BM5. Credit: Nature (2024). DOI: 10.1038/s41586-024-07559-x Researchers at the National Cancer Institute have developed a method called HORNET to characterize the 3D topological structure of large, flexible RNA molecules. The scientists used atomic force microscopy (AFM) with deep neural networks and unsupervised machine learning to capture individual conformers under physiological conditions.…
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Science
Researchers sequence oldest human DNA ever from South Africa
DNA double helix. Credit: Public Domain Researchers have reconstructed the genomes of two humans found in South Africa that lived about 10,000 years ago, providing a better understanding of the conditions in which people in the region lived, the study authors announced Sunday. Victoria Gibbon, professor of biological anthropology at the University of Cape Town (UCT), said the genetic sequence…
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