selectively
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Chemistry
Research provides a scaffolding to selectively target drug failure processes
Primary screen for CYP3A4. Credit: Natural Communication (2025). doi:10.1038/s41467-025-58749-8 Cytochrome P450 (CYP) protein degrades more than 80% of all Food and Drug Administration (FDA) approved drugs, reducing their efficacy. However, how to prevent CYP from doing this without target off effects has previously been confusing researchers. Scientists at St. Jude Children’s Research Hospital have designed a new drug framework that…
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Nanotechnology
Water filters with nanoscale channels selectively remove stubborn “eternal chemicals”
Credit: Monash University Traditional water filters struggle to remove smaller PFAS molecules, but the new Monash designed filter changes it. Researchers at Monash University have developed water filter membranes that effectively remove small PFA molecules, overcoming the important challenges faced by traditional water filters. The researchers designed beta-cyclodextrin (βCD)-modified graphene oxide (GO-βCD) membranes using nanoscale channels that selectively retain PFA…
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Chemistry
Chemists develop metal-free method to selectively convert symmetric diols into one of two enantiomers
Internal view of the photoreactor setup in operation. Credit: Science (2024). DOI: 10.1126/science.adq8029 A team of chemists at the University of Cambridge has developed a metal-free method to selectively convert symmetric diols into one of their two enantiomers. In a paper published in the journal Science, the research group exploits the ability of the chiral form of quinuclidine (quinuclidine is…
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Nanotechnology
Light-induced immunoassay can selectively detect coronavirus spike protein in five minutes
A low-power laser induces bubble formation and convection, moving the nanoparticles and accumulating them at assembly sites on the antibody-coated substrate, accelerating detection. Credit: Osaka Metropolitan University/CC BY 4.0 Just as moths are attracted to a flame, microbes can be navigated by light. Using this knowledge, researchers at the Research Institute for Light Acceleration Systems (RILACS), Osaka Metropolitan University, have…
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