repair
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Biology
Study reveals unknown role of RNA in DNA damage repair
Francesca Storici and her research team have discovered the surprising role of RNA in DNA repair, an insight that could lead to better treatments for cancer and other diseases. Credit: Chris McKechnie A multi-institutional team of researchers led by Georgia Tech’s Francesca Storrisi has discovered a previously unknown role for RNA. Their insights could transform our understanding of genetic health…
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Science
Unique mRNA delivery method could repair defective genes before birth
In utero delivery of Cas9 mRNA/gRNA by ADP-LNP leads to extensive cell editing in the fetal brain. Credit: University of California, Davis New research shows that biomedical tools can successfully deliver genetic material to edit defective genes in developing fetal brain cells. The technology, tested in mice, could halt the progression of genetically based neurodevelopmental conditions such as Angelman syndrome…
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