prostate
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Chemistry
Novel platinum complex exhibits potent antiproliferative effects with low toxicity in preclinical prostate cancer models
Binuclear platinum(II) complex inhibits prostate cancer cell proliferation by binding to androgen receptor (AR) and interfering with AR-mediated gene expression. This mechanism causes apoptosis and prevents cell proliferation induced by dihydrotestosterone (DHT). Credit: Yoshihisa Hirota / SIT, Japan. DOI: 10.1021/acs.inorgchem.4c01093 Prostate cancer remains a global health challenge, ranking as the second most commonly diagnosed cancer among men. Although treatments such…
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Nanotechnology
Nanoparticle therapy brings new hope to prostate cancer patients
The wavelength of 810 nm is optimal for energy absorption/excitation of nanoshells (orange) compared to hemoglobin (red) and water (blue). The nanoshell diameter is approximately 150 nm, which is 46 times smaller than a red blood cell (RBC). NIR refers to near-infrared rays. Credit: Journal of Urology (2024). DOI: 10.1097/JU.0000000000004222 Prostate cancer is the second leading cause of cancer death…
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