Phase

Science

Deep Design Produces ‘Butterfly’ Phase Mask for Light Sheet Fluorescence Microscopy

(A) With a conventional Gaussian beam, the illumination beam spreads at its edges due to diffraction. (B) Joint optimization scheme, where the network predicts the position of the beads in the focal plane. The deep learning network and the input phase mask are updated simultaneously based on a loss function. Credit: Chen Li et al. Researchers have presented a solution…