nanobody

Nanotechnology

Scientists develop nanobody inhibitor to target deadly Ebola virus

Structural basis of anti-EBOV function of Nanosota-EB1. (A) Cryo-EM structure of EBOV GP-ΔM in complex with Nanosota-EB1 (top view, surface view). The three subunits of EBOV GP-ΔM are colored orange, gray, and green, respectively. Nanosota-EB1 is shown in blue. Two Nanosota-EB1 molecules are bound to the trimeric GP-ΔM. (B) Cryo-EM structure (side view) of EBOV GP-ΔM in complex with Nanosota-EB1.…