membrane
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Chemistry
Studying membrane proteins using genetic code extensions
Protein labeling strategy. Credit: Chemical Reviews (2024). DOI: 10.1021/acs.chemrev.4c00181 Over the years, chemical biology techniques have made important contributions to the study of integral membrane proteins. An important modern approach is genetic code expansion (GCE), which allows proteins to be directly modified in living cells to confer customized properties. Professor Irene Coyne of the University of Leipzig is a pioneer…
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Biology
Researchers identify a novel endocytic recycling mechanism via ‘kiss-and-run’ membrane fusion
Identification of intracellular clathrin-associated carriers that transiently visit the plasma membrane. Credit: Nature Cell Biology (2024). DOI: 10.1038/s41556-024-01499-4 Endocytosis and recycling control the uptake and retrieval of a variety of materials in eukaryotic cells. Mammalian cells have developed several recycling pathways, including the “fast” and “slow” tubular vesicle recycling pathways, which have been relatively extensively studied. However, endocytic recycling pathways…
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