kilogramscale
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Chemistry
Drum Mill achieves kilogram-scale ibuprofen synthesis with environmentally friendly technology
Co-crystal powder (rac-ibuprofen nicotinamide) and milling ball IMPACTIVE. Credit: Jan-Hendrik Schöbel For the first time, researchers have used a drum mill to produce kilograms of ibuprofen-nicotinamide, a formulation that improves therapeutic efficacy and stability. This is part of the European project IMPACTIVE, which focuses on researching mechanochemical methods to make pharmaceutical manufacturing more sustainable and reduce both carbon emissions and…
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