enzymes

  • BiologyA Pair Of Rare Enzymes In Marine Microorganisms Could Boost

    A pair of rare enzymes in marine microorganisms could boost carbon storage

    Characteristics of cyanobacteria with multiple Rubisco types. (A) Ribosomal protein tree showing the ODZ Prochlorococcus lineage and its Rubisco. (B) Form II Rubisco gene tree showing representative AMZ IB sequences and their phylogenetic background. The tips of the trees are labeled with sequence numbers (Dataset S2). (C) Maximum carboxylation rate (kcat) of type II rubiscos reported in ref. AMZ IB…

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  • BiologyTesting Of Thousands Of Rna Enzymes Discovers First 'twister Ribozyme'

    Testing of thousands of RNA enzymes discovers first ‘Twister ribozyme’ in mammals

    A novel cleavage high-throughput assay (CHiTA) developed at Penn State University provides a flawless method to characterize thousands of diverse small self-cleaving RNA enzymes called Twister ribozymes in a single experiment. This image shows 2D models of some of the ribozymes tested that had defects in the helical and loop elements but still remained active, demonstrating that the Twister ribozyme’s…

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  • ChemistryNatural Compounds In Flowers Block The Activity Of Enzymes Linked

    Natural compounds in flowers block the activity of enzymes linked to multiple sclerosis and cancer

    Structure of flavonoids extracted from dahlia and coreopsis flowers. Red boxes indicate similarities between compound structures and sulfretin (A), and blue boxes indicate differences. Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.107916 Scientists have identified a natural compound that halts processes involved in the development of certain forms of cancer and demyelinating conditions, such as multiple sclerosis, that damage the…

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  • ChemistryGlowing Proteins Enable Real Time 3d Studies Of Essential Enzymes

    Glowing proteins enable real-time 3D studies of essential enzymes

    Graphical summary. Credit: Nature Chemical Biology (2024). DOI: 10.1038/s41589-024-01758-3 Researchers at the University of California, San Diego School of Medicine have developed a new tool to use organoid models to study the protein kinase C (PKC) enzyme, which plays a critical role in cell growth, differentiation, and survival. Dysfunction of these proteins has been linked to many human diseases, including…

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