disease
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Nanotechnology
Nanoparticles restore Parkinson’s disease neurons with wireless brain stimulation
A practical model demonstrating wireless DBS mediated by ATB NPs to reverse PD. Credit: Science Advances (2025). DOI: 10.1126/sciadv.ado4927 Parkinson’s disease (PD) is the second most common neurodegenerative disease and is primarily characterized by motor dysfunction. Its pathological hallmark is the abnormal aggregation of α-synuclein (α-syn) into insoluble fibrils and Lewy bodies, which causes degeneration and death of dopaminergic neurons…
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Biology
Surprising discovery sheds light on the cause of Huntington’s disease, a deadly brain disorder
This micrograph provided by the Harvard Brain Tissue Resource Center at McLean Hospital in January 2024 shows cells within the caudate nucleus structure of the brain of a patient with Huntington’s disease. Credit: Harvard Brain Tissue Resource Center at McLean Hospital/NIH NeuroBioBank (via AP) Scientists are unraveling the mysteries that trigger Huntington’s disease. Huntington’s disease is a devastating and fatal…
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Nanotechnology
Detecting disease with a single molecule: Nanopore-based sensors could transform diagnostics
The sensor is a glass tube whose tip is melted into a sharp needle-like structure that is immersed in a liquid containing molecules. Credit: Kevin Freedman/ImageFX/UCR Scientists at the University of California, Riverside have developed a nanopore-based tool that can diagnose diseases much faster and more accurately than current tests by capturing signals from individual molecules. The molecules that scientists…
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Nanotechnology
Mechanical engineers find a way to increase the sensitivity of nanopores for early disease detection
Credit: Analytical Chemistry (2024). DOI: 10.1021/acs.analchem.4c02016 SMU Lyle Mechanical Engineering graduate student Kamruzzaman Jyoti will introduce new techniques in nanotechnology to detect and analyze biomolecules, potentially paving the way for new methods for early disease detection. The research, recently featured on the cover of Analytical Chemistry, integrates octahedral DNA origami structures with solid-state nanopores to significantly improve detection of proteins,…
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Nanotechnology
Scientists develop copper depletion strategy for advanced cuprococcal disease treatment
Credit: Chemical Sciences (2024). DOI: 10.1039/D4SC04712E A research team from Nanjing University introduced an innovative approach to copper ptosis treatment by depleting copper levels within tumor cells, challenging the current paradigm focused on copper overproduction. The study, published in the journal Chemical Science, uses mesoporous zinc sulfide (ZnS) nanoparticles as “copper nanoconsumers” to efficiently remove copper ions from cancer cells.…
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Nanotechnology
Team develops non-invasive biosensor for early detection of kidney disease
Researchers have developed a biosensor that uses affinity peptides to detect symmetrical dimethylarginine (SDMA), an early marker of kidney problems. This sensor measures SDMA levels in urine with high accuracy, making it a practical and cost-effective tool for early diagnosis and monitoring. Credit: “Kidney Cross Section” Artwork: Holly Fischer Image Source: https://commons.wikimedia.org/w/index.php?curid=24367128 Traditionally, kidney health has been monitored by measuring…
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Environment
AI models predict diarrheal disease outbreaks related to climate change
Credit: Pixabay/CC0 Public Domain Extreme weather events related to climate change, such as massive floods and prolonged droughts, often cause dangerous outbreaks of diarrheal diseases, especially in developing countries, and diarrheal diseases are the third leading cause of death in young children. It becomes. A study published in Environmental Research Letters on October 22, 2024, by an international research team…
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