Discovery
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Chemistry
Smarter and faster AI models explored for molecular and material discovery
Computational strategies for material generation. Credit: Nature Computational Science (2025). doi:10.1038/s43588-025-00797-7 Cornell researchers demonstrate how artificial intelligence, particularly deep learning and generation modeling, can accelerate the design of new molecules and materials, and act as autonomous research assistants. In a study published in Advanced Science, researchers explored ways to make AI models more efficient and effective in predicting molecular properties…
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Physics
Machine learning approaches lead to discovery of high-performance infrared functional materials
Schematic diagram of a synergistic framework for interpretable ML-assisted target synthesis of IRFM. Credit: Advanced Science (2025). doi:10.1002/advs.202417851 Infrared photoelectronic functional materials are essential for lasers, photodetectors and infrared imaging applications, and form the technical backbone of modern optoelectronics. Traditionally, the development of new infrared materials has relied heavily on trial and error experimental methods. However, these approaches are inefficient…
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Chemistry
An efficient selection platform enables discovery of novel lysine targeting covalent inhibitors
Credit: Pixabay/CC0 Public Domain In a study published in Angewandte Chemie International Edition, the researchers integrated activity-based protein profiling (ABPP) data with covalent DNA-encoding chemical library (Codel) technology to identify structurally novel lysine target covalent inhibitors with diverse mechanisms of action. The team is led by Lu Xiaojie of the Shanghai Institute of Materials and Media, China Academy of Sciences,…
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Science
The discovery of Kina technology challenges the view of ancient human development in East Asia
Kina technology was discovered in Europe decades ago, but has never been discovered in East Asia before. Credit: Ben Marwick The Mid-Lestic Age is considered a dynamic period in European and African history, but is generally considered a static period in East Asia. New research at the University of Washington challenges that perception. Researchers have discovered the complete Kina technical…
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Other Sciences
Melsonby’s Reservoir: Iron Age Yorkshire Discovery reveals ancient British connections to Europe
Credit: Durham University Melsonby’s Reservoir is an astonishing collection of over 800 Iron Age metal artifacts discovered in December 2021 in a field near Melsonby, North Yorkshire. The discovery represents the victory of cross-sector cooperation in British archaeology. This extraordinary discovery, excavated from Yorkshire soil, is not only a collection of ancient objects, but also shows the need for important…
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Other Sciences
Saturday Quote: A confused discovery from Webb. Early human faces. Humans and dogs like to cool them down together
The left midface fossils of humanity from 1.1 million to 1.4 million years ago have recovered from the site of Sima del Elephante in simulations of Sierra de Atapuerc, Burgos, Spain, and the opposite mirror. Credits: Maria D. Guillen/Iphes-Cerca, Elena Santos/Cenieh This week we reported a difficult experience of humans trying to read dog emotions. Researchers reported that male blue-lined…
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Biology
The discovery of molecular “springs” reveals how hearing is caused
3D models help researchers to better understand the structure and function of the mechanical springs of ion channels. From left to right: Professor Martin Gepfert, Dr. Thomas Effert, Dr. Philip Herat. Credit: Philip Hehlert Auditation begins with the elongation of the elastic molecule “springs,” which open ion channels to the sensory hair cells of the ear. For decades, researchers knew…
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Chemistry
Unexpected discovery of collagen structures indicates greater diversity than previously believed
Characterization of A, B-CRT and C peptide assemblies: Credit: ACS Central Science (2025). doi:10.1021/accentsci.5c00018 Collagen, the body’s most abundant protein, has long been considered a predictable structural component of tissue. However, a new study led by Jeffrey Hartgarin and Tracy Yu of Rice University, in collaboration with Mark Kreuzberger and Edward Egelman of the University of Virginia (UVA) is likely…
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Biology
Surprising discovery sheds light on the cause of Huntington’s disease, a deadly brain disorder
This micrograph provided by the Harvard Brain Tissue Resource Center at McLean Hospital in January 2024 shows cells within the caudate nucleus structure of the brain of a patient with Huntington’s disease. Credit: Harvard Brain Tissue Resource Center at McLean Hospital/NIH NeuroBioBank (via AP) Scientists are unraveling the mysteries that trigger Huntington’s disease. Huntington’s disease is a devastating and fatal…
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Science
Fossil discovery sheds light on the early evolution of animal nervous systems
An incomplete tubular specimen of the Eopliaprites sphinx excavated from the Quang Tuanh Formation of the Early Cambrian. The ventral nerve cord is shown. Credit: Science Advances (2025). DOI: 10.1126/sciadv.adr0896 An international team of scientists has solved a fascinating piece of the evolutionary puzzle. That’s how the ventral nerve cord, a key component of the central nervous system, evolved in…
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