Colorchanging

Chemistry

Color-changing fluorescent dyes allow for accurate temperature measurements within living cells

A novel single fluorophore ratiometric fluorotherm developed using solvent-dyed dyes achieved record sensitivity and enabled live cells and environmental sensing. Credit: Science Tokyo Temperature is an important variable that affects countless biological processes at the cellular level. However, accurate measurement of temperature within living cells remains difficult. Traditional temperature measurement techniques often lack the spatial resolution required to detect subtle…