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Collaborative research elucidates the mechanism of African plants that have anti-HIV effects

Chemical structure of the components of Croton megalobotrys Müll Arg (Namushen-1 and Namushen-2). Similarity to the reference protein kinase C activator Prostratin is shown. The substructure of protein kinase C activator/modulator (prostratin) is highlighted with the chemical structure of the phorbol ester from mukungul. Credit: Journal of Experimental Pharmacology (2024). DOI: 10.2147/JEP.S472234 A joint study between the Wistar Institute and…