cancer
-
Nanotechnology
Scientists design stable protein complexes for targeted cancer therapy
Credit: ACS Nano (2024). DOI: 10.1021/acsnano.4c09220 Auburn University researchers, in partnership with the University of Basel in Switzerland, have discovered a new way to make cancer-targeting protein complexes more stable, opening the door to better cancer treatments. . The study, led by Dr. Rafael Bernardi of Auburn University’s Department of Physics and Dr. Michael Nash of the Department of Chemistry…
Read More » -
Chemistry
Researchers discover that chemicals in Cordyceps sinensis may slow the growth of cancer cells
A caterpillar infected with Cordyceps sinensis, a beautiful orange fungus that produces Cordyceps sinensis (cordycepin). Credit: Daniel Winkler – Mushroaming New research into a chemical produced by a caterpillar fungus that holds promise as a potential cancer treatment reveals how it interacts with genes and blocks cell growth signals. This discovery is an important step toward developing new drugs that…
Read More » -
Chemistry
Natural compounds in flowers block the activity of enzymes linked to multiple sclerosis and cancer
Structure of flavonoids extracted from dahlia and coreopsis flowers. Red boxes indicate similarities between compound structures and sulfretin (A), and blue boxes indicate differences. Credit: Journal of Biological Chemistry (2024). DOI: 10.1016/j.jbc.2024.107916 Scientists have identified a natural compound that halts processes involved in the development of certain forms of cancer and demyelinating conditions, such as multiple sclerosis, that damage the…
Read More » -
Nanotechnology
Nanoparticle therapy brings new hope to prostate cancer patients
The wavelength of 810 nm is optimal for energy absorption/excitation of nanoshells (orange) compared to hemoglobin (red) and water (blue). The nanoshell diameter is approximately 150 nm, which is 46 times smaller than a red blood cell (RBC). NIR refers to near-infrared rays. Credit: Journal of Urology (2024). DOI: 10.1097/JU.0000000000004222 Prostate cancer is the second leading cause of cancer death…
Read More » -
Chemistry
Scientists discover chemical probe for previously ‘untreatable’ cancer target
Structural models predict that the small molecule binding site on FOXA1 is close to DNA. Credit: Scripps Research Cancers caused by hormones, such as breast and prostate cancers, often rely on a difficult-to-target protein called forkhead box protein 1 (FOXA1). FOXA1 mutations may enable these types of cancers to grow and proliferate. Currently, FOXA1 is notoriously difficult to block with…
Read More » -
Nanotechnology
New microchip captures exosomes, enabling faster and more sensitive lung cancer detection from blood collection
The twisted disc shape of gold nanoparticles creates chirality, or asymmetry, and ensures strong interaction with light. A cavity in the center, less than 100 nanometers wide, helps the nanoparticles trap exosomes. Credit: University of Michigan A new method for diagnosing lung cancer by drawing blood is 10 times faster and 14 times more sensitive than previous methods, according to…
Read More » -
Nanotechnology
Researchers develop new covalent organic framework for precise targeting of cancer treatment
Credit: ACS Applied Materials & Interfaces (2024). DOI: 10.1021/acsami.4c10812 A team of researchers at New York University Abu Dhabi (NYUAD), led by Chemistry Program Director Ali Trabolsi, has developed nanoscale covalent organic frameworks (nCOFs), crystalline organic polymers modified with peptides, to treat the most aggressive form of breast cancer called triple-negative breast cancer (TNBC). The peptides enable the COF to…
Read More » -
Nanotechnology
Improved nano-sized cell particles discovered to enhance cancer immunotherapy and reduce side effects
Electron micrograph of artificial extracellular vesicles (magnification 23,000x). Courtesy: NUS Yong Loo Lin School of Medicine Immunotherapy is a type of cancer treatment that uses the body’s own immune system to fight cancer. It stimulates an immune response to more effectively recognize and attack cancer cells. Treatments may involve using substances to boost the immune system, teaching immune cells to…
Read More »
