bacterial
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Biology
Foreign DNA ‘slips’ through bacterial defenses, promoting antibiotic resistance
Credit: Nature (2024). DOI: 10.1038/s41586-024-07994-w A new study from Tel Aviv University has revealed how bacterial defense mechanisms are disabled, allowing efficient transfer of genetic material between bacteria. Researchers believe this discovery could pave the way for the development of tools to address the antibiotic resistance crisis and facilitate more effective genetic engineering methods for medical, industrial and environmental purposes.…
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Biology
Targeting bacterial defense mechanisms for effective antibiotic treatment
Possible causes of mortality upon loss of membrane potential. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-51347-0 In addition to the urgent need for new antibiotics, alternative strategies are also needed to tackle the problem of antibiotic resistance. Associate Professor Michaela Wenzel of Chalmers University of Technology studies bacterial defenses against external stress and targets these for efficient antibiotic treatments. Michaela Wenzel…
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Chemistry
Team develops promising new form of antibiotic that causes bacterial cells to self-destruct
Credit: Journal of Medicinal Chemistry (2024). DOI: 10.1021/acs.jmedchem.4c00773 To address the global threat of antibiotic resistance, scientists are exploring new ways to bypass bacterial cell defense systems. Researchers at the University of Toronto (U of T) have used what they learned from previous research on cancer to develop a new compound that causes bacterial cells to self-destruct. The research team’s…
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