Physics

Image-guided computational holographic wavefront shaping: a fast and versatile solution to complex imaging challenges

Microscopic images of cells using a conventional light microscope (left) and images processed using a new technology (right). Credit: Omri Haim and Jeremy Boger-Lombard

A study published in Nature Photonics by researchers at the Hebrew University of Jerusalem’s Institute of Applied Physics introduces a new method for non-invasive high-resolution imaging using highly scattering media.

The team, led by Professor Ori Katz, Omri Haim, and Jeremy Boger-Lombard, will introduce holography-based computational techniques to address key challenges in the field of optical imaging, and will be used in a variety of fields including medical imaging, autonomous imaging, and more. Opens new doors to applications. vehicle and microscope.

In this study, we introduce a guide star-free approach that eliminates the need for traditional tools such as high-resolution spatial light modulators (SLMs) and extensive measurements to image through complex scattering media with unprecedented speed and precision. It allows you to become By computationally emulating a wavefront shaping experiment, this new technology optimizes multiple “virtual SLMs” simultaneously, allowing the system to reconstruct high-quality images without requiring prior information about the target or scattering pattern. I will make it possible.

The main achievements are as follows.

High versatility and flexibility: The method can correct over 190,000 scattering modes using only 25 holographically captured scattered light fields obtained under unknown random illumination. This new technology provides flexibility across a variety of imaging modalities, including epi-illumination, multiconjugate correction of scattering layers, and lensless endoscopy. Reduced computational complexity and memory demands: Unlike traditional techniques that require calculation of the entire reflection matrix, this innovative approach significantly reduces memory allocation, speeds up the imaging process, and reduces complex scattering Allows for faster and more effective correction. Cross-disciplinary applications: This study shows the potential for this technology to be applied in various fields such as biological tissue imaging, multicore fiber endoscopy, and even acousto-optic tomography. This method is also expected to provide solutions in fields such as geophysics, radar, and medical ultrasound.

“We are pleased to be able to introduce a new approach in imaging technology that allows high-resolution imaging through highly scattering media without requiring prior knowledge of the target or expensive equipment and with orders of magnitude fewer measurements than state-of-the-art techniques. “I’m excited,” Professor Katz said. “This innovation shifts the challenge from physical hardware to computational optimization and provides a naturally parallelizable solution that can be applied to many fields.”

This research provides a fast, non-invasive, and highly adaptable solution for imaging in complex environments and has the potential to transform key areas of scientific research and real-world applications. The research team is already exploring future directions, including optimizing the method for continuous volume samples, such as thick biological tissue, and further reducing the number of holograms needed.

More information: Image-guided Computational Holographic Wavefront Shaping, Nature Photonics (2024). DOI: 10.1038/s41566-024-01544-6

Provided by Hebrew University of Jerusalem

Citation: Image-Guided Computational Holographic Wavefront Formation: A Fast, Versatile Solution to Complex Imaging Challenges (October 18, 2024) https://phys.org/news/2024-10-image-holographic-wavefront- Retrieved October 19, 2024 from fast-versatile.html

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